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761.
Immunolocalization of caveolin-1 in rat and human mesothelium. 总被引:1,自引:0,他引:1
Christopher J von Ruhland Lee Campbell Mark Gumbleton Bharat Jasani Geoffrey R Newman 《The journal of histochemistry and cytochemistry》2004,52(11):1415-1425
Flask-shaped vesicles have been described as caveolae in mesothelial cells in a number of animal species based on morphological criteria only. Using an antibody against caveolin-1, said to be a biochemical marker of caveolae, immunoelectron microscopy suggests that many but not all such vesicles in mesothelial cells are caveolae. Mesothelial cells from different anatomical sites showed obvious variations in both the population density and distribution of these flask-shaped vesicles and in their density of immunostaining. Lung and pericardial sac had the highest staining density. In some sites (e.g., lung, bladder, colon) caveolae were equally distributed between apical and basolateral surfaces, whereas in others (e.g., spleen, liver), they were predominantly apical. Additional immunopositive sites in the peritoneal membrane were identified, including the epineurium of peripheral nerves and the endothelium of lymphatic vessels. We further suggest that variations in the number of mesothelial cell caveolae and the density of their immunolabeling may have implications for our understanding of certain diseases such as malignant mesothelioma, especially in view of the recent hypothesis that it may be caused by SV40, a virus that appears to enter cells via caveolae. 相似文献
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S K Patnaik 《Biochemistry international》1990,21(1):175-184
The activities and induction patterns of the isoenzymes of alanine aminotransferase (AAT) of the cerebral hemispheres and cerebellum of rats of various ages were studied. The activities of both the soluble (s-) and mitochondrial (m-) isoenzymes of ATT of the cerebral hemispheres and cerebellum were highest in the immature rat and decreased significantly thereafter with increasing age. Adrenalectomy decreased, and hydrocortisone administration increased significantly, the activity of s-AAT in both cerebral hemispheres and cerebellum of immature, adult, and senescent rats. However, these treatments resulted in significant changes in the activity of m-AAT in both tissues of the immature rat only. The hormone-mediated induction of these isoenzymes was actinomycin D-sensitive. 相似文献
766.
Summary The qualitative and quantitative nature of microfungi in soil after burning was studied for seven months. The numbers of fungal species and their colonies in soil were reduced immediately after burning but returned to their normal state after about a couple of months. Species of Aspergillus and Penicillium were the first to colonize the burnt soil. Trichoderma viride appeared after two months. Penicillium spp. decreased consistently with time whereas T. viride followed the reverse path. Several other species appeared in due course as and when ecological conditions became suitable for them. re]19760720 相似文献
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